deltatrials
Recruiting EARLY_PHASE1 INTERVENTIONAL 1-arm NCT06008275

Neratinib in Combination With Ruxolitinib in Patients With mTNBC

Pilot Clinical Trial Examining the Safety and Efficacy of Neratinib in Combination With Ruxolitinib in Patients With Chemotherapy-pretreated Metastatic Triple Negative Breast Cancer With Chest Wall Recurrence

Sponsor: Baylor Research Institute

Updated 7 times since 2023 Last updated: Nov 5, 2025 Started: Sep 16, 2024 Primary completion: Jun 30, 2026 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A EARLY_PHASE1 clinical study on Breast Cancer and Metastatic Triple-Negative Breast Carcinoma, this trial is actively recruiting participants. The trial is conducted by Baylor Research Institute and has accumulated 7 data snapshots since 2024. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshotNot Yet Recruiting~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotNot Yet Recruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Dec 2025 · 13 months · monthly snapshotRecruiting~Dec 2025 – present · 7 months · monthly snapshotRecruiting

Change History

7 versions recorded
  1. Dec 2025 — Present [monthly]

    Recruiting EARLY_PHASE1

  2. Nov 2024 — Dec 2025 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet RecruitingRecruiting

  3. Sep 2024 — Nov 2024 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  4. Aug 2024 — Sep 2024 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  5. Jul 2024 — Aug 2024 [monthly]

    Not Yet Recruiting EARLY_PHASE1

Show 2 earlier versions
  1. Dec 2023 — Jul 2024 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  2. Sep 2023 — Dec 2023 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Baylor Research Institute
Data source: Baylor Research Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations