The Comparison Between Ringer Lactate Solution and Normal Saline With Dextrose Water in Post-Operative Period of Kidney Transplantation (RINNOR)
The Comparison Between Ringer Lactate Solution and Normal Saline With Dextrose Water in the First Week Post-Operative Period of Deceased Donor and Living Donor Kidney Transplantation
Sponsor: King Chulalongkorn Memorial Hospital
This observational or N/A phase trial investigates Electrolyte Imbalance and Kidney Transplant; Complications and is currently completed. King Chulalongkorn Memorial Hospital leads this study, which shows 9 recorded versions since 2024 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.
Status Flow
Change History
9 versions recorded-
Apr 18, 2026 — Present [daily]
Completed
Status: Active Not Recruiting → Completed · Phase: PHASE3 → None
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Feb 2026 — Apr 2026 [monthly]
Active Not Recruiting PHASE3
Status: Completed → Active Not Recruiting
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Jan 2026 — Feb 2026 [monthly]
Completed PHASE3
Status: Recruiting → Completed
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Feb 2025 — Jan 2026 [monthly]
Recruiting PHASE3
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Nov 2024 — Feb 2025 [monthly]
Recruiting PHASE3
Status: Not Yet Recruiting → Recruiting
▶ Show 4 earlier versions
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Sep 2024 — Nov 2024 [monthly]
Not Yet Recruiting PHASE3
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Jul 2024 — Sep 2024 [monthly]
Not Yet Recruiting PHASE3
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Apr 2024 — Jul 2024 [monthly]
Not Yet Recruiting PHASE3
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Oct 2023 — Apr 2024 [monthly]
Not Yet Recruiting PHASE3
First recorded
Eligibility Summary
This is a randomized controlled pragmatic clinical trial. We aim to evaluate the effect of Ringer lactate solution (RLS) and normal saline solution (NSS) with dextrose water (D5W) on the electrolyte abnormality of kidney transplant recipients (KTR) during the first post-operative week. The problem with using NSS with or without D5W as a standard replacement fluid is the hyperchloremic metabolic acidosis which might compromise the kidney allograft function. A total 60 KTR will be enrolled and randomized to receive either RLS or NSS with D5W. The primary outcome is serum bicarbonate level at day 5 after transplantation. Secondary outcomes include the serum potassium, serum sodium, serum chloride, cytokine panel, and the incidence of delayed graft function.
Contact Information
- King Chulalongkorn Memorial Hospital
For direct contact, visit the study record on ClinicalTrials.gov .