deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT06114940

Perioperative TORIPALIMAB Plus LENVATINIB in Patients With Renal Cell Carcinoma Undergoing Nephrectomy (PLUTO) (PLUTO)

PLUTO: A Prospective Phase II Study of Perioperative TORIPALIMAB Plus LENVATINIB in Patients With Renal Cell Carcinoma Undergoing Nephrectomy

Sponsor: Jinling Hospital, China

Updated 8 times since 2023 Last updated: Mar 3, 2026 Started: Dec 20, 2022 Primary completion: Jan 10, 2026 Completion: Jan 10, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Involving changes to the primary endpoint, it is difficult to unify the evaluation criteria for subjects' endpoints before and after the change.

A PHASE2 clinical study on Renal Cell Carcinoma (RCC), this trial is terminated or withdrawn. The trial is conducted by Jinling Hospital, China and has accumulated 8 data snapshots since 2022. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Dec 2023 – ~May 2024 · 5 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotRecruiting~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Nov 2025 · 8 months · monthly snapshotRecruiting~Nov 2025 – ~Mar 2026 · 4 months · monthly snapshotRecruiting~Mar 2026 – present · 4 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Mar 2026 — Present [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  2. Nov 2025 — Mar 2026 [monthly]

    Recruiting PHASE2

  3. Mar 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  4. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE2

  5. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE2

Show 3 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  2. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  3. Dec 2023 — May 2024 [monthly]

    Recruiting PHASE2

    First recorded

Dec 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Jinling Hospital, China
Data source: Jinling Hospital, China

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations