deltatrials
Terminated PHASE2 INTERVENTIONAL 4-arm NCT06818305

Efficacy and Safety of Finerenone and Empagliflozin in Delaying Renal Function Progression After Radical Nephrectomy in High-Risk CKD Patients: A Multicenter RCT (EmFin-Nx)

A Multicenter, Open-Label, Factorial Design, Randomized Controlled Study to Explore the Efficacy and Safety of Finerenone and Empagliflozin, Alone or in Combination, in Delaying Renal Function Progression in High-Risk CKD Patients After Radical Nephrectomy for Renal Cell Carcinoma

Sponsor: Jinling Hospital, China

Updated 2 times since 2025 Last updated: Dec 4, 2025 Started: Jan 1, 2025 Primary completion: Oct 1, 2025 Completion: Oct 1, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The patient enrollment rate is proceeding too slowly

A PHASE2 clinical study on Chronic Kidney Disease(CKD) and Nephrectomy, this trial is terminated or withdrawn. The trial is conducted by Jinling Hospital, China and has accumulated 2 data snapshots since 2025. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Mar 2025 – ~Jan 2026 · 10 months · monthly snapshotRecruiting~Jan 2026 – present · 6 months · monthly snapshotTerminated

Change History

2 versions recorded
  1. Jan 2026 — Present [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  2. Mar 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

    First recorded

Jan 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Jinling Hospital, China
  • Qilu Hospital of Shandong University
  • The Affiliated Hospital of Xuzhou Medical University
  • The First Affiliated Hospital with Nanjing Medical University
  • Yantai Yuhuangding Hospital
Data source: Jinling Hospital, China

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations