deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT06192108

A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin (ACHIEVE-2)

A Phase 3, Randomized, Open-Label Study to Investigate the Efficacy and Safety of Once Daily Oral Orforglipron Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin (ACHIEVE-2)

Sponsor: Eli Lilly and Company

Updated 18 times since 2024 Last updated: Oct 16, 2025 Started: Jan 10, 2024 Primary completion: Sep 26, 2025 Completion: Sep 26, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Type 2 Diabetes and is currently completed. Eli Lilly and Company leads this study, which shows 18 recorded versions since 2024 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jun 2024 · 2 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshotCompleted

Change History

18 versions recorded
  1. Dec 2025 — Present [monthly]

    Completed PHASE3

  2. Nov 2025 — Dec 2025 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Sep 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Jun 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

Show 13 earlier versions
  1. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Mar 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  4. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE3

  5. Nov 2024 — Jan 2025 [monthly]

    Recruiting PHASE3

  6. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  7. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  8. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  9. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  10. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  11. Apr 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  12. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE3

  13. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE3

    First recorded

Jan 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .