deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT00052936

Combination Chemotherapy With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma

Randomised Study Comparing 6 And 8 Cycles Of Chemotherapy With CHOP ( Cyclophosphamide, Doxorubicin, Vincristine And Prednisone) At 14-Day Intervals (CHOP-14), Both With Or Without The Monoclonal Anti-CD20 Antibody Rituximab In Patients Aged 61 To 80 Years With Aggressive Non-Hodgkin's Lymphoma

Sponsor: German High-Grade Non-Hodgkin's Lymphoma Study Group

Conditions Lymphoma
Interventions CHOP regimen cyclophosphamide doxorubicin hydrochloride filgrastim prednisone radiation therapy rituximab vincristine sulfate
Updated 7 times since 2017 Last updated: May 14, 2021 Started: Jan 31, 2001 Primary completion: Aug 5, 2010 Completion: Aug 5, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Lymphoma, this trial is completed. The trial is conducted by German High-Grade Non-Hodgkin's Lymphoma Study Group and has accumulated 7 data snapshots since 2001. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotUnknown Status~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotUnknown Status~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotUnknown Status~Jun 2021 – ~Jul 2024 · 37 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jun 2021 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Unknown Status → Completed

  5. Jan 2021 — Jun 2021 [monthly]

    Unknown Status PHASE3

▶ Show 2 earlier versions

  1. Jun 2018 — Jan 2021 [monthly]

    Unknown Status PHASE3

  2. Jan 2017 — Jun 2018 [monthly]

    Unknown Status PHASE3

    First recorded

Jan 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • German High-Grade Non-Hodgkin's Lymphoma Study Group
Data source: Universität des Saarlandes

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Amberg, Germany , Ansbach, Germany , Aschaffenburg, Germany , Augsburg, Germany , Aurich, Germany , Bad Hersfeld, Germany , Bad Saarow, Germany , Bayreuth, Germany , Berlin, Germany and 117 more locations