deltatrials
Completed PHASE1 INTERVENTIONAL 4-arm NCT06285240

Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Assess the Safety, Tolerability, and Pharmacokinetics of MK-1167 Administered to Patients With Alzheimer's Disease Receiving Stable Donepezil Treatment

Sponsor: Merck Sharp & Dohme LLC

Updated 10 times since 2024 Last updated: Sep 23, 2025 Started: Mar 28, 2024 Primary completion: Sep 23, 2024 Completion: Sep 23, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Alzheimer's Disease and is currently completed. Merck Sharp & Dohme LLC leads this study, which shows 10 recorded versions since 2024 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Sep 2025 · 11 months · monthly snapshotCompleted~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2025 — Nov 2025 [monthly]

    Completed PHASE1

  3. Oct 2024 — Sep 2025 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  4. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

Show 5 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  2. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  3. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  4. Apr 2024 — May 2024 [monthly]

    Not Yet Recruiting PHASE1

  5. Mar 2024 — Apr 2024 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .