deltatrials
Active Not Recruiting PHASE3 NCT06411288

Global Study of Del-desiran for the Treatment of DM1

A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Global Study to Evaluate the Efficacy and Safety of Intravenous AOC 1001 for the Treatment of Myotonic Dystrophy Type 1

Sponsor: Avidity Biosciences, Inc.

Updated 15 times since 2024 Last updated: Jan 20, 2026 Started: May 30, 2024 Primary completion: Aug 31, 2026 Completion: Sep 30, 2026

This PHASE3 trial investigates DM1 and Dystrophy Myotonic and is currently ongoing. Avidity Biosciences, Inc. leads this study, which shows 15 recorded versions since 2024 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Change History

15 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  4. Jun 2025 — Aug 2025 [monthly]

    Recruiting PHASE3

  5. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

Show 10 earlier versions
  1. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE3

  2. Mar 2025 — Apr 2025 [monthly]

    Recruiting PHASE3

  3. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE3

  4. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE3

  5. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE3

  6. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

  7. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  8. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  9. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  10. Jun 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

May 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Avidity Biosciences, Inc.
Data source: Avidity Biosciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aarhus N, Denmark, Aomori, Japan, Baltimore, United States, Boston, United States, Cincinnati, United States, Columbus, United States, Copenhagen, Denmark, Denver, United States, Donostia / San Sebastian, Spain, Durham, United States and 22 more location s