deltatrials
Recruiting PHASE3 INTERVENTIONAL 3-arm NCT06472245

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor (ARTEMIA)

A Randomised, Open-label, Phase 3 Trial Comparing the Efficacy and Safety of OSE2101 Versus Docetaxel in HLA-A2 Positive Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) With Secondary Resistance to Immune Checkpoint Inhibitor

Sponsor: Exystat

Updated 12 times since 2024 Last updated: Mar 4, 2026 Started: Dec 3, 2024 Primary completion: Dec 15, 2027 Completion: Dec 15, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Patients With Non-Small Cell Lung Cancer and is currently actively recruiting participants. Exystat leads this study, which shows 12 recorded versions since 2024 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotNot Yet Recruiting~Jan 2025 – ~Mar 2025 · 59 days · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshotRecruiting~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshotRecruiting~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Mar 2026 · 59 days · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshotRecruiting

Change History

12 versions recorded
  1. Mar 2026 — Present [monthly]

    Recruiting PHASE3

  2. Jan 2026 — Mar 2026 [monthly]

    Recruiting PHASE3

  3. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE3

  4. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

  5. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE3

Show 7 earlier versions
  1. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

  2. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  3. Jun 2025 — Aug 2025 [monthly]

    Recruiting PHASE3

  4. Mar 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

  5. Jan 2025 — Mar 2025 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  6. Sep 2024 — Jan 2025 [monthly]

    Not Yet Recruiting PHASE3

  7. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Exystat
  • Genome Diagnostics (GenDx)
  • OSE Immunotherapeutics
Data source: OSE Immunotherapeutics

For direct contact, visit the study record on ClinicalTrials.gov .