Not Yet Recruiting PHASE2 INTERVENTIONAL 4-arm NCT06580444

Brexanolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study

Brexanolone to Target Concurrent Posttraumatic Stress Disorder (PTSD) and Stress Induced Alcohol Use in Veterans: A Dose Finding Study

Sponsor: Congressionally Directed Medical Research Programs

Conditions Alcohol Use Disorder (AUD) Post Traumatic Stress Disorder (PTSD)

Interventions Brexanolone

Updated 3 times since 2024 Last updated: May 27, 2025 Started: Jul 28, 2025 Primary completion: Feb 26, 2027 Completion: Mar 19, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Alcohol Use Disorder (AUD) and Post Traumatic Stress Disorder (PTSD), this trial is actively recruiting participants. The trial is conducted by Congressionally Directed Medical Research Programs and has accumulated 3 data snapshots since 2025. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

3 versions recorded

Jun 2025 — Present [monthly]

Not Yet Recruiting PHASE2
Mar 2025 — Jun 2025 [monthly]

Not Yet Recruiting PHASE2
Sep 2024 — Mar 2025 [monthly]

Not Yet Recruiting PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Congressionally Directed Medical Research Programs
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
RTI International
Sage Therapeutics
United States Department of Defense
VA Connecticut Healthcare System
Yale University

Data source: Pharmacotherapies for Alcohol and Substance Use Disorders Alliance

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.