deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 1-arm NCT05223829

Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Interventions Brexanolone
Updated 15 times since 2022 Last updated: Oct 8, 2025 Started: Aug 1, 2023 Primary completion: Dec 31, 2025 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Alcohol Use Disorder and PTSD, this trial is ongoing. The trial is conducted by National Institute on Alcohol Abuse and Alcoholism (NIAAA) and has accumulated 15 data snapshots since 2023. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshot~Nov 2023 – ~Mar 2024 · 4 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Jul 2025 · 4 months · monthly snapshot~Jul 2025 – ~Nov 2025 · 4 months · monthly snapshot~Nov 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded
  1. Nov 2025 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Jul 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Mar 2025 — Jul 2025 [monthly]

    Recruiting PHASE1

  4. Dec 2024 — Mar 2025 [monthly]

    Recruiting PHASE1

  5. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

Show 10 earlier versions
  1. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  2. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  3. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  4. Nov 2023 — Mar 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  5. Aug 2023 — Nov 2023 [monthly]

    Not Yet Recruiting PHASE1

  6. Apr 2023 — Aug 2023 [monthly]

    Not Yet Recruiting PHASE1

  7. Feb 2023 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE1

  8. Sep 2022 — Feb 2023 [monthly]

    Not Yet Recruiting PHASE1

  9. Jun 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE1

  10. Mar 2022 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute on Alcohol Abuse and Alcoholism (NIAAA)
  • Sage Therapeutics
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations