Completed NA INTERVENTIONAL 2-arm NCT06608030

Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery

Effect of a Single Dose of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery: a Randomized Controlled Trial

Sponsor: Beijing Tiantan Hospital

Conditions Cardiac Surgery Depression, Anxiety S-ketamine

Interventions Esketamine normal saline

Updated 5 times since 2024 Last updated: Nov 23, 2025 Started: Sep 23, 2024 Primary completion: Apr 7, 2025 Completion: Apr 30, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06608030, this NA trial focuses on Cardiac Surgery and Depression, Anxiety and remains completed. Sponsored by Beijing Tiantan Hospital, it has been updated 5 times since 2024, reflecting limited change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

Change History

5 versions recorded

Dec 2025 — Present [monthly]

Completed NA

Status: Recruiting → Completed
Sep 2025 — Dec 2025 [monthly]

Recruiting NA
Feb 2025 — Sep 2025 [monthly]

Recruiting NA
Dec 2024 — Feb 2025 [monthly]

Recruiting NA

Status: Not Yet Recruiting → Recruiting
Oct 2024 — Dec 2024 [monthly]

Not Yet Recruiting NA

First recorded

Sep 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Beijing Tiantan Hospital
Chinese PLA General Hospital
The Sixth Medical Center of Chinese PLA General Hospital

Data source: Chinese PLA General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Beijing, China