deltatrials
Recruiting INTERVENTIONAL NCT06676319

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma (AIRLYMPUS)

A Randomized, Phase 2, Double-blind, Placebo-controlled, Parallel-group, 2-arm Study to Investigate the Efficacy, Safety, and Tolerability of Subcutaneous Lunsekimig (SAR443765) in Adult Participants With High-risk Asthma Who Are Not Currently Eligible for Biologic Treatment

Sponsor: Sanofi

Conditions Asthma
Updated 15 times since 2024 Last updated: Apr 15, 2026 Started: Nov 7, 2024 Primary completion: Sep 17, 2027 Completion: Oct 15, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06676319, this observational or N/A phase trial focuses on Asthma and remains actively recruiting participants. Sponsored by Sanofi, it has been updated 15 times since 2024, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshotRecruiting~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Apr 2026 · 2 months · monthly snapshotRecruitingApr 17, 2026 – present · 4 months · daily APIRecruiting

Change History

15 versions recorded
  1. Apr 17, 2026 — Present [daily]

    Recruiting

    Phase: PHASE2None

  2. Feb 2026 — Apr 2026 [monthly]

    Recruiting PHASE2

  3. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE2

  4. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

  5. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE2

Show 10 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE2

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  4. Jun 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

  5. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE2

  6. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE2

  7. Mar 2025 — Apr 2025 [monthly]

    Recruiting PHASE2

  8. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE2

  9. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE2

  10. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE2

    First recorded

Nov 2024

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

This is a parallel-group, Phase 2, randomized, double-blind, placebo-controlled, 2-arm study for the treatment of asthma. The purpose of this study is to assess the efficacy, safety, and tolerability of add-on therapy with subcutaneous (SC) lunsekimig compared with placebo in male and female participants (aged 18 to 80 years, inclusive) with asthma, who are not currently eligible for biologic treatments. Study details include: * The study duration will be approximately 64 weeks for participants not transitioning into the LTS study and approximately 60 weeks for participants transitioning into the LTS study. * The investigational treatment duration will be up to approximately 52 weeks. * The number of visits will be 18.

Contact Information

Sponsor contact:
  • Sanofi
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .