deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT06785454

A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension

A Phase 2, Multicenter, Randomized, Double Blind, Placebo Controlled, Crossover Study to Evaluate the Efficacy and Safety of Lorundrostat in Participants With Moderate to Severe Obstructive Sleep Apnea and Hypertension

Sponsor: Mineralys Therapeutics Inc.

Updated 6 times since 2025 Last updated: Jan 12, 2026 Started: Feb 28, 2025 Primary completion: Dec 17, 2025 Completion: Dec 29, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Hypertension and Obstructive Sleep Apnea and is currently completed. Mineralys Therapeutics Inc. leads this study, which shows 6 recorded versions since 2025 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Feb 2025 – ~Jun 2025 · 4 months · monthly snapshotNot Yet Recruiting~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshotRecruiting~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshotRecruiting~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshotActive Not Recruiting~Feb 2026 – present · 6 months · monthly snapshotCompleted

Change History

6 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Nov 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  4. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  5. Jun 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

Show 1 earlier version
  1. Feb 2025 — Jun 2025 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mineralys Therapeutics Inc.
Data source: Mineralys Therapeutics Inc.

For direct contact, visit the study record on ClinicalTrials.gov .