deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 3-arm NCT05968430

Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension

An Open-Label Extension Study to Assess the Long-Term Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension

Sponsor: Mineralys Therapeutics Inc.

Conditions Hypertension
Updated 24 times since 2023 Last updated: Feb 13, 2026 Started: Jul 14, 2023 Primary completion: Dec 30, 2025 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05968430, this PHASE3 trial focuses on Hypertension and remains ongoing. Sponsored by Mineralys Therapeutics Inc., it has been updated 24 times since 2023, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 6 months · monthly snapshot

Change History

24 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: Enrolling By InvitationActive Not Recruiting

  5. Apr 2025 — Jun 2025 [monthly]

    Enrolling By Invitation PHASE3

Show 19 earlier versions
  1. Mar 2025 — Apr 2025 [monthly]

    Enrolling By Invitation PHASE3

  2. Feb 2025 — Mar 2025 [monthly]

    Enrolling By Invitation PHASE3

  3. Jan 2025 — Feb 2025 [monthly]

    Enrolling By Invitation PHASE3

  4. Dec 2024 — Jan 2025 [monthly]

    Enrolling By Invitation PHASE3

  5. Nov 2024 — Dec 2024 [monthly]

    Enrolling By Invitation PHASE3

    Status: RecruitingEnrolling By Invitation

  6. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  7. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  8. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

    Phase: PHASE2/PHASE3PHASE3

  9. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  10. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2_PHASE3

  11. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE2_PHASE3

  12. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE2_PHASE3

  13. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE2_PHASE3

  14. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE2_PHASE3

  15. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE2_PHASE3

  16. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE2_PHASE3

  17. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE2_PHASE3

  18. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE2_PHASE3

  19. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Jul 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mineralys Therapeutics Inc.
Data source: Mineralys Therapeutics Inc.

For direct contact, visit the study record on ClinicalTrials.gov .