deltatrials
Recruiting INTERVENTIONAL NCT07023627

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression (MAESTRA 1)

A Phase 2, Single-Arm Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression (MAESTRA 1)

Sponsor: ENGOT Foundation

Conditions Ovarian Cancer
Interventions INCB123667
Updated 9 times since 2025 Last updated: Apr 10, 2026 Started: Nov 12, 2025 Primary completion: Apr 27, 2027 Completion: Oct 24, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Ovarian Cancer and is currently actively recruiting participants. ENGOT Foundation leads this study, which shows 9 recorded versions since 2025 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Apr 2026 · 2 months · monthly snapshotRecruitingApr 16, 2026 – present · 4 months · daily APIRecruiting

Change History

9 versions recorded
  1. Apr 16, 2026 — Present [daily]

    Recruiting

    Phase: PHASE2None

  2. Feb 2026 — Apr 2026 [monthly]

    Recruiting PHASE2

  3. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE2

  4. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

  5. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE2

Show 4 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Aug 2025 — Sep 2025 [monthly]

    Not Yet Recruiting PHASE2

  4. Jul 2025 — Aug 2025 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

This study will evaluate the safety and efficacy of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer (PROC) With Cyclin E1 Overexpression.

Contact Information

Sponsor contact:
  • ENGOT Foundation
  • GOG Foundation
  • Incyte Corporation
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .