deltatrials
Not Yet Recruiting PHASE1 INTERVENTIONAL 3-arm NCT07101328

A Study of LY4152199 in Participants With Previously Treated B-cell Cancers (BAF_FRontier-1 ) (BAF_FRontier-1)

BAF_FRontier-1, A First-in-Human, Phase 1 Trial to Assess Safety, Tolerability, and Preliminary Efficacy of LY4152199, a B-cell Activation Factor Receptor (BAFF-R) T-Cell Engager Bispecific Antibody in Adult Participants With Previously Treated B-cell Malignancies

Sponsor: Eli Lilly and Company

Interventions LY4152199 - IV
Updated 7 times since 2025 Last updated: Mar 2, 2026 Started: Jun 30, 2026 Primary completion: Apr 30, 2027 Completion: Mar 31, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on B-cell Lymphoma and Lymphoma, Follicular, this trial is actively recruiting participants. The trial is conducted by Eli Lilly and Company and has accumulated 7 data snapshots since 2026. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshotNot Yet Recruiting~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshotNot Yet Recruiting~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshotNot Yet Recruiting~Mar 2026 – present · 5 months · monthly snapshotNot Yet Recruiting

Change History

7 versions recorded
  1. Mar 2026 — Present [monthly]

    Not Yet Recruiting PHASE1

  2. Feb 2026 — Mar 2026 [monthly]

    Not Yet Recruiting PHASE1

  3. Jan 2026 — Feb 2026 [monthly]

    Not Yet Recruiting PHASE1

  4. Dec 2025 — Jan 2026 [monthly]

    Not Yet Recruiting PHASE1

  5. Nov 2025 — Dec 2025 [monthly]

    Not Yet Recruiting PHASE1

Show 2 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Not Yet Recruiting PHASE1

  2. Sep 2025 — Oct 2025 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .