Completed PHASE3 INTERVENTIONAL 2-arm NCT00028743

Combination Chemotherapy Regimens in Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

A Phase III Study of Cisplatin Plus Topotecan Followed by Paclitaxel Plus Carboplatin Versus Paclitaxel Plus Carboplatin as First Line Chemotherapy in Women With Newly Diagnosed Advanced Epithelial Ovarian Cancer

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Conditions Fallopian Tube Cancer Ovarian Cancer Peritoneal Cavity Cancer

Interventions carboplatin cisplatin paclitaxel topotecan hydrochloride

Updated 7 times since 2017 Last updated: Mar 31, 2020 Started: Aug 31, 2001 Primary completion: Mar 5, 2008 Completion: Jan 10, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Fallopian Tube Cancer and Ovarian Cancer and is currently completed. European Organisation for Research and Treatment of Cancer - EORTC leads this study, which shows 7 recorded versions since 2001 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
May 2020 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Jun 2018 — May 2020 [monthly]

Completed PHASE3
Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Aug 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

European Organisation for Research and Treatment of Cancer - EORTC
Grupo Español de Investigación en Cáncer de Ovario
NCIC Clinical Trials Group

Data source: Canadian Cancer Trials Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Calgary, Canada , Charlottetown, Canada , Edmonton, Canada , Greater Sudbury, Canada , Halifax, Canada , Hamilton, Canada , Kelowna, Canada , Kingston, Canada , Kitchener, Canada , London, Canada and 17 more locations