deltatrials
Terminated PHASE1 INTERVENTIONAL NCT00238173

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Phase I Dose Escalation Study of N-Acetylcysteine Administered in Conjunction With Carboplatin, Cyclophosphamide, and Etoposide Phosphate BBBD, in Children With Malignant Brain Tumors

Sponsor: National Cancer Institute (NCI)

Updated 7 times since 2017 Last updated: Apr 19, 2017 Started: Dec 31, 2004 Primary completion: Feb 17, 2006 Completion: Feb 17, 2006
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

OHSU IRB closed study to further enrollment 2/17/2006

This PHASE1 trial investigates Bone Marrow Suppression and Brain and Central Nervous System Tumors and is currently terminated or withdrawn. National Cancer Institute (NCI) leads this study, which shows 7 recorded versions since 2004 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotSuspended~Feb 2017 – ~May 2017 · 3 months · monthly snapshotSuspended~May 2017 – ~Jun 2018 · 13 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 24 months · monthly snapshotTerminated

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE1

  4. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE1

  5. May 2017 — Jun 2018 [monthly]

    Terminated PHASE1

    Status: SuspendedTerminated

Show 2 earlier versions
  1. Feb 2017 — May 2017 [monthly]

    Suspended PHASE1

  2. Jan 2017 — Feb 2017 [monthly]

    Suspended PHASE1

    First recorded

Dec 2004

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • OHSU Knight Cancer Institute
Data source: OHSU Knight Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations