deltatrials
Completed PHASE3 NCT00265759

Exemestane, Letrozole, or Anastrozole in Treating Postmenopausal Women Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer

A Randomized Phase III Trial Comparing 16 to 18 Weeks of Neoadjuvant Exemestane (25 mg Daily), Letrozole (2.5 mg), or Anastrozole (1 mg) in Postmenopausal Women With Clinical Stage II and III Estrogen Receptor Positive Breast Cancer

Sponsor: Alliance for Clinical Trials in Oncology

Conditions Breast Cancer
Updated 11 times since 2017 Last updated: Apr 4, 2025 Started: Jan 31, 2006 Primary completion: Aug 31, 2012 Completion: Nov 27, 2019

A PHASE3 clinical study on Breast Cancer, this trial is completed. The trial is conducted by Alliance for Clinical Trials in Oncology and has accumulated 11 data snapshots since 2006. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~May 2017 · 3 months · monthly snapshotActive Not Recruiting~May 2017 – ~Jun 2018 · 13 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Aug 2019 · 14 months · monthly snapshotActive Not Recruiting~Aug 2019 – ~Mar 2020 · 7 months · monthly snapshotActive Not Recruiting~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~May 2025 · 8 months · monthly snapshotCompleted~May 2025 – ~Sep 2025 · 4 months · monthly snapshotCompleted~Sep 2025 – present · 7 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. May 2025 — Sep 2025 [monthly]

    Completed PHASE3

  3. Sep 2024 — May 2025 [monthly]

    Completed PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. Mar 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Aug 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE3

  3. Jun 2018 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  4. May 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  5. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Jan 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alliance for Clinical Trials in Oncology
  • Cancer and Leukemia Group B
  • National Cancer Institute (NCI)
Data source: Alliance for Clinical Trials in Oncology

For direct contact, visit the study record on ClinicalTrials.gov .