deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT00485472

Trial to Assess Efficacy and Safety of Lacosamide in Subjects With Osteoarthritis of the Knee

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Osteoarthritis of the Knee

Sponsor: UCB Pharma

Conditions Osteoarthritis
Updated 12 times since 2017 Last updated: Jul 28, 2017 Started: Mar 31, 2007 Primary completion: Nov 30, 2007 Completion: Jan 31, 2008
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Based on the outcome of the planned first interim analysis, it was decided not to continue the trial. No safety concerns were identified.

This PHASE2 trial investigates Osteoarthritis and is currently terminated or withdrawn. UCB Pharma leads this study, which shows 12 recorded versions since 2007 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotTerminated~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshotTerminated~Sep 2017 – ~May 2018 · 8 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 7 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  2. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE2

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE2

  4. Sep 2017 — May 2018 [monthly]

    Terminated PHASE2

  5. Aug 2017 — Sep 2017 [monthly]

    Terminated PHASE2

  6. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE2

    First recorded

Mar 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • UCB Pharma
Data source: UCB Pharma

For direct contact, visit the study record on ClinicalTrials.gov .