deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT00529438

RTA 402 in Patients With Advanced Solid Tumors or Lymphoid Malignancies

A Phase I Dose-finding and Pharmacokinetic Study of RTA 402 (CDDOMe) Administered Orally for 21 Days of a 28-day Cycle in Patients With Advanced Solid Tumors or Lymphoid Malignancies

Sponsor: Biogen

Interventions Bardoxolone methyl
Updated 9 times since 2017 Last updated: May 22, 2025 Started: Apr 30, 2006 Primary completion: Dec 1, 2008 Completion: Dec 1, 2008
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Advanced Solid Tumors and Lymphoid Malignancies, this trial is completed. The trial is conducted by Biogen and has accumulated 9 data snapshots since 2006. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Nov 2023 · 34 months · monthly snapshotCompleted~Nov 2023 – ~Mar 2024 · 4 months · monthly snapshotCompleted~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshotCompleted~Jun 2025 – present · 15 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Jun 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Jun 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Mar 2024 — Jul 2024 [monthly]

    Completed PHASE1

  5. Nov 2023 — Mar 2024 [monthly]

    Completed PHASE1

Show 4 earlier versions
  1. Jan 2021 — Nov 2023 [monthly]

    Completed PHASE1

  2. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

  3. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE1

  4. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1

    First recorded

Apr 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Biogen
Data source: Biogen

For direct contact, visit the study record on ClinicalTrials.gov .