deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00777101

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer

A Phase 2 Randomized Open-Label Study of Neratinib Versus Lapatinib Plus Capecitabine For The Treatment Of ErbB-2 Positive Locally Advanced Or Metastatic Breast Cancer

Sponsor: Puma Biotechnology, Inc.

Updated 10 times since 2017 Last updated: Jul 11, 2018 Started: Feb 4, 2009 Primary completion: Mar 31, 2011 Completion: Jun 3, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00777101, this PHASE2 trial focuses on Advanced Breast Cancer and Breast Cancer and remains completed. Sponsored by Puma Biotechnology, Inc., it has been updated 10 times since 2009, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Dec 2017 · 10 months · monthly snapshotActive Not Recruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotActive Not Recruiting~Sep 2018 – ~Jan 2021 · 28 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE2

Show 5 earlier versions
  1. Sep 2018 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE2

  3. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2017 — Dec 2017 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Feb 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Puma Biotechnology, Inc.
Data source: Puma Biotechnology, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .