deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00866918

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia

Risk Adapted Treatment of Newly Diagnosed Childhood Acute Promyelocytic Leukemia (APL) Using Arsenic Trioxide (Trisenox® ) During Consolidation

Sponsor: Children's Oncology Group

Updated 13 times since 2017 Last updated: Oct 3, 2022 Started: Mar 9, 2009 Primary completion: Jun 30, 2015 Completion: Sep 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00866918, this PHASE3 trial focuses on Childhood Acute Promyelocytic Leukemia With PML-RARA and Myeloid Neoplasm and remains completed. Sponsored by Children's Oncology Group, it has been updated 13 times since 2009, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2018 · 13 months · monthly snapshot~Jun 2018 – ~Oct 2019 · 16 months · monthly snapshot~Oct 2019 – ~Apr 2020 · 6 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Apr 2022 · 12 months · monthly snapshot~Apr 2022 – ~Nov 2022 · 7 months · monthly snapshot~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 9 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Nov 2022 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Apr 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE3

Show 8 earlier versions
  1. Apr 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: Unknown StatusActive Not Recruiting

  2. Jan 2021 — Apr 2021 [monthly]

    Unknown Status PHASE3

  3. Apr 2020 — Jan 2021 [monthly]

    Unknown Status PHASE3

    Status: CompletedUnknown Status

  4. Oct 2019 — Apr 2020 [monthly]

    Completed PHASE3

  5. Jun 2018 — Oct 2019 [monthly]

    Completed PHASE3

  6. May 2017 — Jun 2018 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  7. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Mar 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Oncology Group
  • National Cancer Institute (NCI)
Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .