deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT00867568

TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma

A Phase 1 Trial of TPI 287 as a Single Agent and in Combination With Temozolomide in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma

Sponsor: Cortice Biosciences, Inc.

Interventions TPI 287
Updated 10 times since 2017 Last updated: Aug 2, 2024 Started: Mar 31, 2009 Primary completion: Sep 30, 2011 Completion: Feb 29, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Medulloblastoma and Neuroblastoma, this trial is completed. The trial is conducted by Cortice Biosciences, Inc. and has accumulated 10 data snapshots since 2009. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~May 2022 · 16 months · monthly snapshotCompleted~May 2022 – ~Oct 2023 · 17 months · monthly snapshotCompleted~Oct 2023 – ~May 2024 · 7 months · monthly snapshotCompleted~May 2024 – ~Jul 2024 · 2 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 9 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. May 2024 — Jul 2024 [monthly]

    Completed PHASE1

  5. Oct 2023 — May 2024 [monthly]

    Completed PHASE1

Show 5 earlier versions
  1. May 2022 — Oct 2023 [monthly]

    Completed PHASE1

  2. Jan 2021 — May 2022 [monthly]

    Completed PHASE1

  3. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

  4. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE1

  5. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1

    First recorded

Mar 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cortice Biosciences, Inc.
  • Giselle Sholler
Data source: Milton S. Hershey Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .