deltatrials
Suspended PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT01933815

Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma

Phase 1/2 Dose-Escalation Study of TPI 287 in Combination With Bevacizumab Followed by Randomized Study of the Maximum Tolerated Dose of TPI 287 in Combination With Bevacizumab Versus Bevacizumab Alone in Adults With Recurrent Glioblastoma

Sponsor: Cortice Biosciences, Inc.

Updated 11 times since 2017 Last updated: Feb 21, 2023 Started: Aug 31, 2013 Primary completion: Nov 30, 2024 Completion: May 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Suspended

Business reasons

This PHASE1/PHASE2 trial investigates Glioblastoma Multiforme and is currently suspended. Cortice Biosciences, Inc. leads this study, which shows 11 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~May 2018 · 15 months · monthly snapshotRecruiting~May 2018 – ~Jun 2018 · 31 days · monthly snapshotSuspended~Jun 2018 – ~Dec 2020 · 30 months · monthly snapshotSuspended~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotSuspended~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotSuspended~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshotSuspended~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshotSuspended~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotSuspended~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotSuspended~Sep 2025 – present · 10 months · monthly snapshotSuspended

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Suspended PHASE1/PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Suspended PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Suspended PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Mar 2023 — Jul 2024 [monthly]

    Suspended PHASE1_PHASE2

  5. Sep 2022 — Mar 2023 [monthly]

    Suspended PHASE1_PHASE2

Show 6 earlier versions
  1. Jan 2021 — Sep 2022 [monthly]

    Suspended PHASE1_PHASE2

  2. Dec 2020 — Jan 2021 [monthly]

    Suspended PHASE1_PHASE2

  3. Jun 2018 — Dec 2020 [monthly]

    Suspended PHASE1_PHASE2

  4. May 2018 — Jun 2018 [monthly]

    Suspended PHASE1_PHASE2

    Status: RecruitingSuspended

  5. Feb 2017 — May 2018 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Aug 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cortice Biosciences, Inc.
Data source: Cortice Biosciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .