deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT02187822

Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases

A Phase 1 Study of TPI 287 Concurrent With Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases From Advanced Breast and Non-Small Cell Lung (NSCL) Cancer

Sponsor: Cortice Biosciences, Inc.

Conditions Brain Lesions Brain Metastases Generalized Malignancy, Primary
Interventions Fractionated Stereotactic Radiotherapy (FSRT) TPI 287
Updated 18 times since 2017 Last updated: Feb 3, 2021 Started: Oct 9, 2014 Primary completion: Feb 20, 2018 Completion: Mar 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

lack of funding by company providing TPI-287

Other terminated trials from Cortice Biosciences, Inc.

More terminations from Cortice Biosciences, Inc.

This PHASE1 trial investigates Brain Lesions and Brain Metastases and is currently terminated or withdrawn. Cortice Biosciences, Inc. leads this study, which shows 18 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Oct 2017 · 5 months · monthly snapshot~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Feb 2019 · 4 months · monthly snapshot~Feb 2019 – ~Jun 2019 · 4 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Dec 2019 · 5 months · monthly snapshot~Dec 2019 – ~May 2020 · 5 months · monthly snapshot~May 2020 – ~Oct 2020 · 5 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jul 2024 · 40 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

18 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Mar 2021 — Jul 2024 [monthly]

    Terminated PHASE1

  4. Jan 2021 — Mar 2021 [monthly]

    Terminated PHASE1

  5. Oct 2020 — Jan 2021 [monthly]

    Terminated PHASE1

▶ Show 13 earlier versions

  1. May 2020 — Oct 2020 [monthly]

    Terminated PHASE1

  2. Dec 2019 — May 2020 [monthly]

    Terminated PHASE1

  3. Jul 2019 — Dec 2019 [monthly]

    Terminated PHASE1

  4. Jun 2019 — Jul 2019 [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

  5. Feb 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE1

  6. Oct 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE1

  7. Jun 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE1

  8. Apr 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: Suspended → Active Not Recruiting

  9. Mar 2018 — Apr 2018 [monthly]

    Suspended PHASE1

  10. Oct 2017 — Mar 2018 [monthly]

    Suspended PHASE1

    Status: Recruiting → Suspended

  11. May 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  12. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE1

  13. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Oct 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cortice Biosciences, Inc.
  • H. Lee Moffitt Cancer Center and Research Institute
Data source: H. Lee Moffitt Cancer Center and Research Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations