Terminated PHASE4 INTERVENTIONAL 2-arm NCT00881205

Rivastigmine in Multiple Sclerosis Patients With Cognitive Impairment (EXCITING)

A 16-week, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy of Rivastigmine Patch (10 cm²) on Cognitive Deficits in Patients With Multiple Sclerosis, Followed by a 1-year Open-label Treatment Phase

Sponsor: Novartis Pharmaceuticals

Conditions Cognitive Impairment Multiple Sclerosis

Interventions Placebo Rivastigmine transdermal patch

Updated 8 times since 2017 Last updated: Mar 8, 2012 Started: Apr 30, 2009 Primary completion: Jan 31, 2011 Completion: Jan 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Termination of study due to low enrollment

This PHASE4 trial investigates Cognitive Impairment and Multiple Sclerosis and is currently terminated or withdrawn. Novartis Pharmaceuticals leads this study, which shows 8 recorded versions since 2009 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Jan 2026 — Present [monthly]

Terminated PHASE4
Sep 2025 — Present [monthly]

Terminated PHASE4
Sep 2024 — Sep 2025 [monthly]

Terminated PHASE4
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE4
Dec 2021 — Jul 2024 [monthly]

Terminated PHASE4

▶ Show 3 earlier versions

Jan 2021 — Dec 2021 [monthly]

Terminated PHASE4
Jun 2018 — Jan 2021 [monthly]

Terminated PHASE4
Jan 2017 — Jun 2018 [monthly]

Terminated PHASE4

First recorded

Apr 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Novartis Pharmaceuticals

Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Aalen, Germany , Abensberg, Germany , Achim, Germany , Alzenau in Unterfranken, Germany , Aschaffenburg, Germany , Bad Mergentheim, Germany , Bayreuth, Germany , Berlin, Germany , Bochum, Germany and 31 more locations