deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02102490

A Study of Abemaciclib (LY2835219) In Participants With Previously Treated Breast Cancer That Has Spread (MONARCH 1)

A Phase 2 Study of LY2835219 for Patients With Previously Treated Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer

Sponsor: Eli Lilly and Company

Interventions Abemaciclib
Updated 15 times since 2017 Last updated: Jan 10, 2020 Started: Jun 10, 2014 Primary completion: Apr 30, 2016 Completion: Oct 22, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Metastatic Breast Cancer and is currently completed. Eli Lilly and Company leads this study, which shows 15 recorded versions since 2014 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Feb 2020 · 4 months · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 9 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Feb 2020 — Jan 2021 [monthly]

    Completed PHASE2

Show 10 earlier versions
  1. Oct 2019 — Feb 2020 [monthly]

    Completed PHASE2

  2. Sep 2019 — Oct 2019 [monthly]

    Completed PHASE2

  3. Apr 2019 — Sep 2019 [monthly]

    Completed PHASE2

  4. Jan 2019 — Apr 2019 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Jun 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  7. Dec 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE2

  8. Jun 2017 — Dec 2017 [monthly]

    Active Not Recruiting PHASE2

  9. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE2

  10. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Jun 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .