deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT02090283

Open-Label Extension Study to Evaluate the Safety of SD-101 Cream in Participants With Epidermolysis Bullosa

An Open Label Extension, Multi-Center, Study to Evaluate the Safety of SD-101 Cream in Subjects With Epidermolysis Bullosa

Sponsor: Amicus Therapeutics

Updated 12 times since 2017 Last updated: Oct 31, 2019 Started: Mar 26, 2014 Primary completion: Sep 14, 2018 Completion: Sep 14, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The Sponsor voluntarily recalled SD-101 and terminated the study due to GMP deficiencies identified during an FDA inspection at the site of the manufacturer.

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This PHASE2 trial investigates Epidermolysis Bullosa and is currently terminated or withdrawn. Amicus Therapeutics leads this study, which shows 12 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~May 2018 · 15 months · monthly snapshotActive Not Recruiting~May 2018 – ~Jun 2018 · 31 days · monthly snapshotActive Not Recruiting~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshotActive Not Recruiting~Dec 2018 – ~Dec 2019 · 12 months · monthly snapshotTerminated~Dec 2019 – ~Nov 2020 · 11 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 7 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  2. Dec 2019 — Nov 2020 [monthly]

    Terminated PHASE2

    Phase: NAPHASE2

  3. Dec 2018 — Dec 2019 [monthly]

    Terminated NA

    Status: Active Not RecruitingTerminated

  4. Jun 2018 — Dec 2018 [monthly]

    Active Not Recruiting NA

  5. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting NA

  6. Feb 2017 — May 2018 [monthly]

    Active Not Recruiting NA

  7. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting NA

    First recorded

Mar 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amicus Therapeutics
  • Food and Drug Administration (FDA)
  • Scioderm, Inc.
Data source: Scioderm, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .