deltatrials
Terminated PHASE3 INTERVENTIONAL 1-arm NCT02670330

Open Label Extension Study to Evaluate the Long-term Safety of Zorblisa (SD-101-6.0) in Patients With Epidermolysis Bullosa

An Open Label Multi-Center Extension Study to Evaluate the Long-term Safety of Zorblisa™ (SD-101-6.0) in Patients With Epidermolysis Bullosa

Sponsor: Amicus Therapeutics

Interventions SD-101-6.0 cream
Updated 13 times since 2017 Last updated: Sep 10, 2019 Started: Jun 9, 2015 Primary completion: Sep 3, 2018 Completion: Sep 3, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The Sponsor voluntarily recalled SD-101 and terminated the study due to GMP deficiencies identified during an FDA inspection at the site of the manufacturer.

Other Epidermolysis Bullosa trials with similar outcome

Browse all Epidermolysis Bullosa trials

This PHASE3 trial investigates Epidermolysis Bullosa and is currently terminated or withdrawn. Amicus Therapeutics leads this study, which shows 13 recorded versions since 2015 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2018 · 13 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Sep 2019 · 10 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2020 · 13 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

Show 8 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Oct 2019 — Nov 2020 [monthly]

    Terminated PHASE3

  3. Sep 2019 — Oct 2019 [monthly]

    Terminated PHASE3

    Phase: NAPHASE3

  4. Nov 2018 — Sep 2019 [monthly]

    Terminated NA

    Status: Active Not RecruitingTerminated

  5. Jun 2018 — Nov 2018 [monthly]

    Active Not Recruiting NA

  6. May 2017 — Jun 2018 [monthly]

    Active Not Recruiting NA

  7. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting NA

  8. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting NA

    First recorded

Jun 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amicus Therapeutics
  • Scioderm, Inc.
Data source: Scioderm, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .