deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT02141399

A Long-Term Safety Study of ALKS 5461

A Phase 3 Multicenter Study of the Long-Term Safety and Tolerability of ALKS 5461 for the Adjunctive Treatment of Major Depressive Disorder in Adults Who Have an Inadequate Response to Antidepressant Therapy (the FORWARD-2 Study)

Sponsor: Alkermes, Inc.

Interventions ALKS 5461
Updated 9 times since 2017 Last updated: Nov 21, 2018 Started: May 31, 2014 Primary completion: Nov 20, 2017 Completion: Nov 20, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02141399, this PHASE3 trial focuses on Major Depressive Disorder and remains completed. Sponsored by Alkermes, Inc., it has been updated 9 times since 2014, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotEnrolling By Invitation~Feb 2017 – ~Jan 2018 · 11 months · monthly snapshotActive Not Recruiting~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshotCompleted~Jan 2019 – ~Jan 2021 · 24 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2019 — Jan 2021 [monthly]

    Completed PHASE3

Show 4 earlier versions
  1. Jun 2018 — Jan 2019 [monthly]

    Completed PHASE3

  2. Jan 2018 — Jun 2018 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Feb 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: Enrolling By InvitationActive Not Recruiting

  4. Jan 2017 — Feb 2017 [monthly]

    Enrolling By Invitation PHASE3

    First recorded

May 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alkermes, Inc.
Data source: Alkermes, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .