deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT02200848

Phase I Study of Lenalidomide, Rituximab and Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

A Phase I Study of Lenalidomide in Combination With Rituximab and Ibrutinib in Relapsed and Refractory CLL and SLL

Sponsor: Georgetown University

Updated 10 times since 2017 Last updated: Jan 10, 2018 Started: Apr 30, 2014 Primary completion: Mar 27, 2017 Completion: Aug 1, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Recruitment difficulties and toxicity

This PHASE1 trial investigates Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma and is currently terminated or withdrawn. Georgetown University leads this study, which shows 10 recorded versions since 2014 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshotRecruiting~Apr 2017 – ~Jun 2017 · 2 months · monthly snapshotSuspended~Jun 2017 – ~Feb 2018 · 8 months · monthly snapshotTerminated~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE1

  5. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE1

Show 5 earlier versions
  1. Feb 2018 — Jun 2018 [monthly]

    Terminated PHASE1

  2. Jun 2017 — Feb 2018 [monthly]

    Terminated PHASE1

    Status: SuspendedTerminated

  3. Apr 2017 — Jun 2017 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

  4. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE1

  5. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Apr 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Georgetown University
  • National Cancer Institute (NCI)
Data source: Georgetown University

For direct contact, visit the study record on ClinicalTrials.gov .