deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT03209401

Niraparib Plus Carboplatin in Patients With Homologous Recombination Deficient Advanced Solid Tumor Malignancies

Sponsor: Georgetown University

Updated 16 times since 2017 Last updated: Feb 1, 2024 Started: Oct 13, 2017 Primary completion: Oct 16, 2023 Completion: Oct 16, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of accrual

A PHASE1 clinical study on Homologous Recombination Deficiency and Solid Tumor, Adult, this trial is terminated or withdrawn. The trial is conducted by Georgetown University and has accumulated 16 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Aug 2017 – ~Nov 2017 · 3 months · monthly snapshot~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Jun 2019 · 9 months · monthly snapshot~Jun 2019 – ~Mar 2020 · 9 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Oct 2021 · 7 months · monthly snapshot~Oct 2021 – ~Sep 2022 · 11 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Nov 2023 · 9 months · monthly snapshot~Nov 2023 – ~Mar 2024 · 4 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Mar 2024 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  5. Nov 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

Show 11 earlier versions
  1. Feb 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  2. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  3. Oct 2021 — Sep 2022 [monthly]

    Recruiting PHASE1

  4. Mar 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  6. Mar 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  7. Jun 2019 — Mar 2020 [monthly]

    Recruiting PHASE1

  8. Sep 2018 — Jun 2019 [monthly]

    Recruiting PHASE1

  9. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

  10. Nov 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  11. Aug 2017 — Nov 2017 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Georgetown University
  • Oregon Health and Science University
  • Tesaro, Inc.
Data source: Georgetown University

For direct contact, visit the study record on ClinicalTrials.gov .