deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT02212015

Evaluation of Votrient in Angiosarcoma (EVA)

Single-arm, Multicenter, Open Label Phase II Trial to Evaluate the Efficacy of Pazopanib in Combination With Paclitaxel in Advanced and Relapsed Angiosarcoma

Sponsor: Hannover Medical School

Conditions Angiosarcoma
Updated 10 times since 2017 Last updated: Jan 21, 2022 Started: Jul 31, 2014 Primary completion: Dec 31, 2019 Completion: Jul 1, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to interim analysis' results and definitions fixed in protocol

A PHASE2 clinical study on Angiosarcoma, this trial is terminated or withdrawn. The trial is conducted by Hannover Medical School and has accumulated 10 data snapshots since 2014. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotRecruiting~Nov 2018 – ~Apr 2020 · 17 months · monthly snapshotRecruiting~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotUnknown Status~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotUnknown Status~Feb 2021 – ~Apr 2022 · 14 months · monthly snapshotTerminated~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Apr 2022 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Feb 2021 — Apr 2022 [monthly]

    Terminated PHASE2

    Status: Unknown StatusTerminated

Show 5 earlier versions
  1. Jan 2021 — Feb 2021 [monthly]

    Unknown Status PHASE2

  2. Apr 2020 — Jan 2021 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

  3. Nov 2018 — Apr 2020 [monthly]

    Recruiting PHASE2

  4. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  5. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hannover Medical School
  • Heidelberg University
  • Helios Klinikum Berlin-Buch
  • Klinikum der Universitaet Muenchen, Grosshadern
  • Medical University Innsbruck
  • Medical University of Graz
  • Medical University of Vienna
  • Novartis Pharmaceuticals
  • University Hospital Dresden
  • University Hospital, Essen
  • Universitätsklinikum Hamburg-Eppendorf
  • Universitätsmedizin Mannheim
Data source: Heidelberg University

For direct contact, visit the study record on ClinicalTrials.gov .