Completed PHASE2 INTERVENTIONAL 3-arm NCT02244606

Oral Ibrexafungerp (SCY-078) vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasis

Open-Label, Randomized Study to Estimate Safety, PK, and Efficacy of Oral Ibrexafungerp (SCY-078) vs. Standard-of-Care Following IV Echinocandin Therapy in the Treatment of Invasive Candidiasis in Hospitalized Nonneutropenic Adults

Sponsor: Scynexis, Inc.

Conditions Candidemia Candidiasis, Invasive Mycoses

Interventions Fluconazole Micafungin SCY-078

Updated 10 times since 2017 Last updated: May 30, 2024 Started: Sep 30, 2014 Primary completion: Jun 30, 2016 Completion: Aug 31, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Candidemia and Candidiasis, Invasive and is currently completed. Scynexis, Inc. leads this study, which shows 10 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 5 earlier versions

Nov 2020 — Jan 2021 [monthly]

Completed PHASE2
Aug 2019 — Nov 2020 [monthly]

Completed PHASE2
Jun 2018 — Aug 2019 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Sep 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Scynexis, Inc.

Data source: Scynexis, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Augusta, United States , Aurora, United States , Baltimore, United States , Birmingham, United States , Butte, United States , Chapel Hill, United States , Charleston, United States , Chicago, United States , Cologne, Germany and 14 more locations