deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02336815

Selinexor Treatment of Refractory Myeloma (STORM)

A Phase 2b, Open-Label, Single-Arm Study of Selinexor (KPT-330) Plus Low-Dose Dexamethasone (Sd) in Patients With Multiple Myeloma Previously Treated With Lenalidomide, Pomalidomide, Bortezomib, Carfilzomib, and an Anti-CD38 Monoclonal Antibody (mAb) Daratumumab, and Refractory to Prior Treatment With Glucocorticoids, an Immunomodulatory Agent, a Proteasome Inhibitor, and an the Anti-CD38 mAb Daratumumab

Sponsor: Karyopharm Therapeutics Inc

Updated 26 times since 2017 Last updated: Jan 24, 2023 Started: May 26, 2015 Primary completion: Jul 26, 2019 Completion: Jul 26, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Multiple Myeloma, this trial is completed. The trial is conducted by Karyopharm Therapeutics Inc and has accumulated 26 data snapshots since 2015. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~May 2019 · 5 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Mar 2020 · 3 months · monthly snapshot~Mar 2020 – ~Sep 2020 · 6 months · monthly snapshot~Sep 2020 – ~Dec 2020 · 3 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

26 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Mar 2022 — Feb 2023 [monthly]

    Completed PHASE2

Show 21 earlier versions
  1. Jan 2022 — Mar 2022 [monthly]

    Completed PHASE2

  2. Jan 2021 — Jan 2022 [monthly]

    Completed PHASE2

  3. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE2

  4. Sep 2020 — Dec 2020 [monthly]

    Completed PHASE2

  5. Mar 2020 — Sep 2020 [monthly]

    Completed PHASE2

  6. Dec 2019 — Mar 2020 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  7. Oct 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2

  8. Aug 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE2

  9. Jun 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE2

  10. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  11. Dec 2018 — May 2019 [monthly]

    Active Not Recruiting PHASE2

  12. Sep 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE2

  13. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE2

  14. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  15. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  16. Dec 2017 — Mar 2018 [monthly]

    Recruiting PHASE2

  17. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  18. Jun 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  19. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  20. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE2

  21. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Karyopharm Therapeutics Inc
Data source: Karyopharm Therapeutics Inc

For direct contact, visit the study record on ClinicalTrials.gov .