To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FALCI)
A Randomized, Double-blind, Phase IIb Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine (FQ) With Artefenomel (OZ439) in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
Sponsor: Medicines for Malaria Venture
Terminated
All treatment arms met the futility criteria for efficacy during the pre-planned interim analysis, therefore the study was stopped.
Other terminated trials from Medicines for Malaria Venture
A PHASE2 clinical study on Plasmodium Falciparum Infection, this trial is terminated or withdrawn. The trial is conducted by Medicines for Malaria Venture and has accumulated 22 data snapshots since 2015. Infectious disease trials contribute critical data for public health response and treatment development.
Status Flow
Change History
22 versions recorded-
Sep 2025 — Present [monthly]
Terminated PHASE2
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Sep 2024 — Sep 2025 [monthly]
Terminated PHASE2
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE2
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Apr 2022 — Jul 2024 [monthly]
Terminated PHASE2
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Dec 2021 — Apr 2022 [monthly]
Terminated PHASE2
▶ Show 17 earlier versions
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Jan 2021 — Dec 2021 [monthly]
Terminated PHASE2
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Nov 2020 — Jan 2021 [monthly]
Terminated PHASE2
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Dec 2019 — Nov 2020 [monthly]
Terminated PHASE2
Status: Recruiting → Terminated
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Nov 2019 — Dec 2019 [monthly]
Recruiting PHASE2
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Oct 2019 — Nov 2019 [monthly]
Recruiting PHASE2
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Sep 2019 — Oct 2019 [monthly]
Recruiting PHASE2
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Jul 2019 — Sep 2019 [monthly]
Recruiting PHASE2
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Nov 2018 — Jul 2019 [monthly]
Recruiting PHASE2
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Aug 2018 — Nov 2018 [monthly]
Recruiting PHASE2
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Jun 2018 — Aug 2018 [monthly]
Recruiting PHASE2
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Feb 2018 — Jun 2018 [monthly]
Recruiting PHASE2
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Dec 2017 — Feb 2018 [monthly]
Recruiting PHASE2
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Sep 2017 — Dec 2017 [monthly]
Recruiting PHASE2
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Aug 2017 — Sep 2017 [monthly]
Recruiting PHASE2
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Jul 2017 — Aug 2017 [monthly]
Recruiting PHASE2
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Feb 2017 — Jul 2017 [monthly]
Recruiting PHASE2
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Jan 2017 — Feb 2017 [monthly]
Recruiting PHASE2
First recorded
Jul 2015
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Medicines for Malaria Venture
- Sanofi
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Bình Phước, Vietnam , Chokwé, Mozambique , Comoé, Burkina Faso , Cotonou, Benin , Kisumu, Kenya , Lambaréné, Gabon , Libreville, Gabon , Niangoloko, Burkina Faso , Ouagadougou, Burkina Faso , Pleiku, Vietnam and 2 more locations