deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT04525014

RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors (PIRATE)

A Phase 1 Trial of RRx-001 in Combination With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors

Sponsor: EpicentRx, Inc.

Updated 15 times since 2020 Last updated: Oct 29, 2024 Started: Jan 26, 2023 Primary completion: Jul 29, 2024 Completion: Jul 29, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Low Enrollment

This PHASE1 trial investigates Brain Tumor, Pediatric and Brain Tumor, Recurrent and is currently terminated or withdrawn. EpicentRx, Inc. leads this study, which shows 15 recorded versions since 2023 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Apr 2024 · 6 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded
  1. Nov 2024 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Nov 2024 [monthly]

    Terminated PHASE1

  3. Aug 2024 — Sep 2024 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  4. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

Show 10 earlier versions
  1. Oct 2023 — Apr 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Aug 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

    Status: Active Not RecruitingRecruiting

  3. May 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Mar 2023 — May 2023 [monthly]

    Recruiting PHASE1

  5. Sep 2022 — Mar 2023 [monthly]

    Recruiting PHASE1

  6. Apr 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  7. Dec 2021 — Apr 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  8. Sep 2021 — Dec 2021 [monthly]

    Not Yet Recruiting PHASE1

  9. Jan 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1

  10. Sep 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • EpicentRx, Inc.
  • Texas Children's Cancer Center
Data source: EpicentRx, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations