deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02892149

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Phase 3, Randomized, Open-Label, Active-Controlled Study Evaluating the Efficacy and Safety of Oral Vadadustat for the Maintenance Treatment of Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) (INNO2VATE-CONVERSION)

Sponsor: Akebia Therapeutics

Updated 27 times since 2017 Last updated: Jun 7, 2022 Started: Aug 31, 2016 Primary completion: Jan 16, 2020 Completion: Mar 30, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02892149, this PHASE3 trial focuses on Anemia and Dialysis-Dependent Chronic Kidney Disease and remains completed. Sponsored by Akebia Therapeutics, it has been updated 27 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Jan 2018 · 3 months · monthly snapshot~Jan 2018 – ~Apr 2018 · 3 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Jul 2020 · 8 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2022 · 14 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Jul 2024 · 24 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

27 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jul 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Apr 2022 — Jul 2022 [monthly]

    Completed PHASE3

Show 22 earlier versions
  1. Feb 2021 — Apr 2022 [monthly]

    Completed PHASE3

  2. Jan 2021 — Feb 2021 [monthly]

    Completed PHASE3

  3. Jul 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Nov 2019 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE3

  6. Aug 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE3

  7. Jul 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  8. Apr 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  9. Jan 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  10. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  11. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  12. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  13. Aug 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  14. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  15. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  16. Jan 2018 — Apr 2018 [monthly]

    Recruiting PHASE3

  17. Oct 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  18. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  19. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  20. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

  21. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE3

  22. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Aug 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Akebia Therapeutics
Data source: Akebia Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .