deltatrials
Completed EARLY_PHASE1 INTERVENTIONAL 2-arm NCT02921893

Ixazomib Citrate, Lenalidomide, and Dexamethasone in Treating Patients With POEMS Syndrome

Ixazomib, Lenalidomide, and Dexamethasone for Patients With POEMS Syndrome

Sponsor: Mayo Clinic

Conditions POEMS Syndrome Plasmacytoma
Interventions Dexamethasone Ixazomib Citrate Lenalidomide Questionnaire Administration
Updated 20 times since 2017 Last updated: Feb 11, 2025 Started: Oct 31, 2016 Primary completion: Apr 21, 2022 Completion: May 13, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A EARLY_PHASE1 clinical study on POEMS Syndrome and Plasmacytoma, this trial is completed. The trial is conducted by Mayo Clinic and has accumulated 20 data snapshots since 2016. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Jun 2020 · 13 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshot~Dec 2022 – ~Nov 2023 · 11 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – present · 16 months · monthly snapshot

Change History

20 versions recorded

  1. Mar 2025 — Present [monthly]

    Completed EARLY_PHASE1

    Status: Active Not Recruiting → Completed

  2. Sep 2024 — Mar 2025 [monthly]

    Active Not Recruiting EARLY_PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting EARLY_PHASE1

  4. Dec 2023 — Jul 2024 [monthly]

    Active Not Recruiting EARLY_PHASE1

  5. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting EARLY_PHASE1

▶ Show 15 earlier versions

  1. Dec 2022 — Nov 2023 [monthly]

    Active Not Recruiting EARLY_PHASE1

  2. Jun 2022 — Dec 2022 [monthly]

    Active Not Recruiting EARLY_PHASE1

    Phase: PHASE2 → EARLY_PHASE1

  3. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Mar 2022 — May 2022 [monthly]

    Recruiting PHASE2

  5. Nov 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

  6. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  7. Apr 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  8. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  9. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  10. May 2019 — Jun 2020 [monthly]

    Recruiting PHASE2

  11. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE2

  12. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  13. Jun 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

    Phase: NA → PHASE2

  14. Feb 2017 — Jun 2017 [monthly]

    Recruiting NA

  15. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Oct 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mayo Clinic
Data source: Mayo Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations