deltatrials
Terminated PHASE3 INTERVENTIONAL 3-arm NCT03085810

Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Participants With Early Stage Relapsing Remitting Multiple Sclerosis (RRMS)

An Open-Label, Single-Arm Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Patients With Early Stage Relapsing Remitting Multiple Sclerosis

Sponsor: Hoffmann-La Roche

Interventions Ocrelizumab
Updated 49 times since 2017 Last updated: Dec 20, 2024 Started: Mar 24, 2017 Primary completion: Apr 27, 2023 Completion: Apr 27, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated earlier as the study sponsor collected sufficient data to perform all analyses as per pre-specified endpoints in the study protocol.

A PHASE3 clinical study on Multiple Sclerosis, Relapsing-Remitting, this trial is terminated or withdrawn. The trial is conducted by Hoffmann-La Roche and has accumulated 49 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2017 – ~Jun 2017 · 2 months · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Nov 2023 · 5 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

49 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Feb 2025 — Sep 2025 [monthly]

    Terminated PHASE3

    Status: CompletedTerminated

  3. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  5. Nov 2023 — Jul 2024 [monthly]

    Completed PHASE3

Show 44 earlier versions
  1. Jun 2023 — Nov 2023 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE3

  3. Mar 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  7. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE3

  8. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  9. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  10. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE3

  11. Mar 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

  12. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

  13. Nov 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE3

  14. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE3

  15. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  16. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  17. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  18. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  19. Sep 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  20. Jun 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  21. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

  22. Feb 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  23. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  24. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  25. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  26. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  27. Aug 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  28. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  29. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  30. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  31. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  32. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  33. Nov 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  34. Sep 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  35. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  36. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  37. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  38. Jan 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  39. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  40. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  41. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  42. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  43. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE3

  44. Apr 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

    First recorded

Mar 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .