deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03105336

A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (ZUMA-5)

A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (iNHL)

Sponsor: Kite, A Gilead Company

Conditions Follicular Lymphoma Indolent Non-Hodgkin Lymphoma Marginal Zone Lymphoma
Interventions Axicabtagene ciloleucel Cyclophosphamide Fludarabine
Updated 46 times since 2017 Last updated: Dec 5, 2025 Started: Jun 6, 2017 Primary completion: Dec 20, 2024 Completion: Dec 20, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Follicular Lymphoma and Indolent Non-Hodgkin Lymphoma and is currently completed. Kite, A Gilead Company leads this study, which shows 46 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Jun 2022 · 9 months · monthly snapshot~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshot~Dec 2022 – ~May 2023 · 5 months · monthly snapshot~May 2023 – ~Oct 2023 · 5 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Mar 2024 · 4 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Feb 2025 · 4 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

46 versions recorded

  1. Jan 2026 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Jan 2026 [monthly]

    Completed PHASE2

  3. Feb 2025 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  4. Oct 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 41 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Nov 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2

  5. May 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Dec 2022 — May 2023 [monthly]

    Active Not Recruiting PHASE2

  7. Jun 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  8. Sep 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  9. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  10. Apr 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  11. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  12. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  14. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  15. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  16. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  17. Aug 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  18. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE2

  19. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  20. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  21. Mar 2020 — May 2020 [monthly]

    Recruiting PHASE2

  22. Jan 2020 — Mar 2020 [monthly]

    Recruiting PHASE2

  23. Oct 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

  24. Jun 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  25. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  26. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  27. Jan 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  28. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  29. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  30. Sep 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  31. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  32. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  33. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  34. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  35. Mar 2018 — Apr 2018 [monthly]

    Recruiting PHASE2

  36. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  37. Jan 2018 — Feb 2018 [monthly]

    Recruiting PHASE2

  38. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  39. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  40. Jun 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  41. May 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kite, A Gilead Company
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Boston, United States , Cleveland, United States , Gilbert, United States , Hackensack, United States , Houston, United States , Lille, France , Los Angeles, United States , Miami, United States , Nashville, United States , New York, United States and 7 more locations