deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT03139370

Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers

A Phase 1 Study Evaluating the Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Subjects With Advanced Cancers

Sponsor: Kite, A Gilead Company

Conditions Solid Tumor
Interventions Cyclophosphamide Fludarabine KITE-718 MAGE - A3/A6 Screening Test
Updated 44 times since 2017 Last updated: Aug 23, 2023 Started: Dec 27, 2017 Primary completion: Jun 30, 2021 Completion: Jun 4, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated due to the sponsor's decision to discontinue the clinical trial.

Other terminated trials from Kite, A Gilead Company

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Listed as NCT03139370, this PHASE1 trial focuses on Solid Tumor and remains terminated or withdrawn. Sponsored by Kite, A Gilead Company, it has been updated 44 times since 2017, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Feb 2018 · 4 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Jan 2019 · 3 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Nov 2022 · 6 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

44 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Sep 2023 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

  4. Jul 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE1

  5. Jun 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE1

▶ Show 39 earlier versions

  1. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

  2. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE1

  3. Feb 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE1

  4. Nov 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1

  5. May 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE1

  6. Mar 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE1

  7. Jan 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

  8. Oct 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  9. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  10. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  11. Mar 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  12. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1

  14. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  15. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

  16. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE1

  17. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

  18. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  19. Jun 2020 — Aug 2020 [monthly]

    Recruiting PHASE1

  20. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1

  21. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1

  22. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  23. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE1

  24. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

  25. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE1

  26. Aug 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

  27. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  28. Apr 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  29. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  30. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1

  31. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE1

  32. Oct 2018 — Jan 2019 [monthly]

    Recruiting PHASE1

  33. Aug 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  34. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  35. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  36. Oct 2017 — Feb 2018 [monthly]

    Recruiting PHASE1

  37. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  38. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE1

  39. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kite, A Gilead Company
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations