Completed PHASE1/PHASE2 INTERVENTIONAL 7-arm NCT03158389

NCT Neuro Master Match - N²M² (NOA-20) (N²M²)

Umbrella Protocol for Phase I/IIa Trials of Molecularly Matched Targeted Therapies Plus Radiotherapy in Patients With Newly Diagnosed Glioblastoma Without MGMT Promoter Methylation: NCT Neuro Master Match - N²M² (NOA-20)

Sponsor: German Cancer Aid

Conditions Glioblastoma, Adult

Interventions APG101 Alectinib Atezolizumab Idasanutlin Palbociclib Temsirolimus Vismodegib

Updated 8 times since 2017 Last updated: Sep 27, 2023 Started: May 7, 2018 Primary completion: Feb 22, 2023 Completion: Feb 22, 2023

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Glioblastoma, Adult, this trial is completed. The trial is conducted by German Cancer Aid and has accumulated 8 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

8 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Oct 2023 — Jul 2024 [monthly]

Completed PHASE1_PHASE2

Status: Recruiting → Completed
Jun 2022 — Oct 2023 [monthly]

Recruiting PHASE1_PHASE2
Jan 2021 — Jun 2022 [monthly]

Recruiting PHASE1_PHASE2

▶ Show 3 earlier versions

Mar 2020 — Jan 2021 [monthly]

Recruiting PHASE1_PHASE2
Jun 2018 — Mar 2020 [monthly]

Recruiting PHASE1_PHASE2

Status: Not Yet Recruiting → Recruiting
Jun 2017 — Jun 2018 [monthly]

Not Yet Recruiting PHASE1_PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

German Cancer Aid
German Cancer Research Center
National Center for Tumor Diseases, Heidelberg
University Hospital Heidelberg

Data source: University Hospital Heidelberg

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Berlin, Germany , Bochum, Germany , Bonn, Germany , Cologne, Germany , Dresden, Germany , Essen, Germany , Frankfurt am Main, Germany , Heidelberg, Germany , Homburg, Germany , Mainz, Germany and 3 more locations