deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT03178032

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

Phase I Trial of DNX-2401 for Diffuse Intrinsic Pontine Glioma Newly Diagnosed in Pediatric Patients.

Sponsor: Alcyone Therapeutics, Inc

Interventions DNX-2401
Updated 12 times since 2017 Last updated: Apr 5, 2023 Started: May 26, 2017 Primary completion: Jan 31, 2021 Completion: Jan 31, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Brainstem Glioma and Neoadjuvant Therapy and is currently completed. Alcyone Therapeutics, Inc leads this study, which shows 12 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jul 2017 – ~May 2019 · 22 months · monthly snapshotRecruiting~May 2019 – ~Sep 2019 · 4 months · monthly snapshotRecruiting~Sep 2019 – ~Mar 2020 · 6 months · monthly snapshotRecruiting~Mar 2020 – ~May 2020 · 2 months · monthly snapshotCompleted~May 2020 – ~Aug 2020 · 3 months · monthly snapshotCompleted~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotActive Not Recruiting~Sep 2022 – ~May 2023 · 8 months · monthly snapshotUnknown Status~May 2023 – ~Jun 2023 · 31 days · monthly snapshotCompleted~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 20 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jun 2023 — Jul 2024 [monthly]

    Completed PHASE1

  4. May 2023 — Jun 2023 [monthly]

    Completed PHASE1

    Status: Unknown StatusCompleted

  5. Sep 2022 — May 2023 [monthly]

    Unknown Status PHASE1

    Status: Active Not RecruitingUnknown Status

Show 7 earlier versions
  1. Jan 2021 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1

  2. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: CompletedActive Not Recruiting

  3. May 2020 — Aug 2020 [monthly]

    Completed PHASE1

  4. Mar 2020 — May 2020 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  5. Sep 2019 — Mar 2020 [monthly]

    Recruiting PHASE1

  6. May 2019 — Sep 2019 [monthly]

    Recruiting PHASE1

  7. Jul 2017 — May 2019 [monthly]

    Recruiting PHASE1

    First recorded

May 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alcyone Therapeutics, Inc
  • Clinica Universidad de Navarra, Universidad de Navarra
  • DNAtrix, Inc.
Data source: Clinica Universidad de Navarra, Universidad de Navarra

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations