deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT04515836

Olaparib in Patients With HRD Malignant Mesothelioma

Phase II Trial of Olaparib in Homologous Recombination Deficient (HRD) Malignant Mesothelioma

Sponsor: AstraZeneca

Interventions Olaparib
Updated 12 times since 2020 Last updated: May 5, 2025 Started: Feb 19, 2021 Primary completion: Apr 15, 2028 Completion: Apr 15, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04515836, this PHASE2 trial focuses on Homologous Recombination Deficiency and Mesothelioma and remains actively recruiting participants. Sponsored by AstraZeneca, it has been updated 12 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshotNot Yet Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshotNot Yet Recruiting~Jun 2021 – ~May 2023 · 23 months · monthly snapshotRecruiting~May 2023 – ~Jul 2024 · 14 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotRecruiting~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshotRecruiting~Nov 2024 – ~Jun 2025 · 7 months · monthly snapshotRecruiting~Jun 2025 – present · 13 months · monthly snapshotRecruiting

Change History

12 versions recorded
  1. Jun 2025 — Present [monthly]

    Recruiting PHASE2

  2. Nov 2024 — Jun 2025 [monthly]

    Recruiting PHASE2

  3. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE2

  4. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

Show 7 earlier versions
  1. May 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Jun 2021 — May 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Feb 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE2

  4. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting PHASE2

  5. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

  6. Oct 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE2

  7. Sep 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • University of Chicago
Data source: University of Chicago

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations