deltatrials
Completed PHASE2 NCT03396926

Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal Cancer

Phase II Study of Pembrolizumab Plus Capecitabine and Bevacizumab in Microsatellite Stable Metastatic Colorectal Cancer

Sponsor: Merck Sharp & Dohme LLC

Updated 16 times since 2018 Last updated: Feb 7, 2025 Started: Apr 18, 2018 Primary completion: Jan 30, 2024 Completion: Jan 30, 2024

Listed as NCT03396926, this PHASE2 trial focuses on Microsatellite Stable and Mismatch Repair Protein Proficient and remains completed. Sponsored by Merck Sharp & Dohme LLC, it has been updated 16 times since 2018, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Feb 2018 – ~May 2018 · 3 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshot~Jun 2019 – ~Apr 2020 · 10 months · monthly snapshot~Apr 2020 – ~Sep 2020 · 5 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Jun 2022 · 9 months · monthly snapshot~Jun 2022 – ~May 2023 · 11 months · monthly snapshot~May 2023 – ~Apr 2024 · 11 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – present · 13 months · monthly snapshot

Change History

16 versions recorded
  1. Mar 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. May 2023 — Apr 2024 [monthly]

    Active Not Recruiting PHASE2

Show 11 earlier versions
  1. Jun 2022 — May 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Sep 2021 — Jun 2022 [monthly]

    Recruiting PHASE2

  3. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  4. Mar 2021 — May 2021 [monthly]

    Recruiting PHASE2

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  6. Sep 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  7. Apr 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

  8. Jun 2019 — Apr 2020 [monthly]

    Recruiting PHASE2

  9. Jun 2018 — Jun 2019 [monthly]

    Recruiting PHASE2

  10. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  11. Feb 2018 — May 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
  • University of California, San Francisco
Data source: University of California, San Francisco

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations