deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT03403725

MEN1309 I.v. Infusion in Pts With CD205-positive Metastatic Solid Tumors and Relapsed or Refractory NHL Ph I Study (CD205SHUTTLE)

Open-Label, Multicenter, Phase I Dose Escalation Study of MEN1309, a CD205 Antibody-Drug Conjugate,in Patients With CD205-Positive Metastatic Solid Tumors and Non-Hodgkin Lymphoma

Sponsor: Menarini Group

Interventions MEN1309
Updated 13 times since 2018 Last updated: Aug 31, 2021 Started: Aug 28, 2017 Primary completion: Oct 22, 2019 Completion: Jan 8, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated after achievement of MTD, without progressing to cohort expansion for Company decision.

This PHASE1 trial investigates Metastatic Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma and is currently terminated or withdrawn. Menarini Group leads this study, which shows 13 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Oct 2019 · 8 months · monthly snapshot~Oct 2019 – ~Apr 2020 · 6 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE1

  5. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE1

Show 8 earlier versions
  1. Dec 2021 — Dec 2022 [monthly]

    Terminated PHASE1

  2. Oct 2021 — Dec 2021 [monthly]

    Terminated PHASE1

  3. Jan 2021 — Oct 2021 [monthly]

    Terminated PHASE1

  4. Apr 2020 — Jan 2021 [monthly]

    Terminated PHASE1

    Status: RecruitingTerminated

  5. Oct 2019 — Apr 2020 [monthly]

    Recruiting PHASE1

  6. Feb 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  7. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  8. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    First recorded

Aug 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Menarini Group
Data source: Menarini Group

For direct contact, visit the study record on ClinicalTrials.gov .