deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 1-arm NCT03523442

A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer

A Phase 1 Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Subjects With Metastatic Castration-Resistant Prostate Cancer

Sponsor: Janssen Research & Development, LLC

Conditions Prostatic Neoplasms
Interventions Apalutamide
Updated 61 times since 2018 Last updated: Mar 12, 2026 Started: Aug 31, 2018 Primary completion: Jul 9, 2019 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03523442, this PHASE1 trial focuses on Prostatic Neoplasms and remains ongoing. Sponsored by Janssen Research & Development, LLC, it has been updated 61 times since 2018, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Sep 2019 · 3 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Jun 2020 · 5 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 2 months · monthly snapshot

Change History

61 versions recorded

  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Feb 2026 — Mar 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2026 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  4. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE1

  5. Nov 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE1

▶ Show 56 earlier versions

  1. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE1

  5. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

  6. Apr 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE1

  7. Mar 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE1

  8. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE1

  9. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1

  10. Nov 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE1

  11. Oct 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE1

  12. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1

  13. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  14. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE1

  15. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  16. May 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE1

  17. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE1

  18. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE1

  19. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE1

  20. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE1

  21. Dec 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE1

  22. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1

  23. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE1

  24. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE1

  25. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE1

  26. Jun 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE1

  27. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

  28. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE1

  29. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE1

  30. Feb 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE1

  31. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1

  32. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE1

  33. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE1

  34. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE1

  35. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1

  36. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

  37. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

  38. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE1

  39. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE1

  40. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

  41. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

  42. Dec 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE1

  43. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE1

  44. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE1

  45. Jan 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

  46. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  47. Jun 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE1

  48. Jan 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE1

  49. Sep 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE1

  50. Jun 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  51. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  52. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  53. Nov 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  54. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  55. Sep 2018 — Oct 2018 [monthly]

    Not Yet Recruiting PHASE1

  56. Jun 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Research & Development, LLC
Data source: Janssen Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations